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heartvalve - Heart Valve They can become diseased and need...

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Heart Valve They can become diseased and need replacement. About 250,000 are done each year. They narrow (stenosis) or leak. Your choices are: a homograft, another valve from your own heart or other tissue fashioned into a valve. an allograft: from a cadaver a heterograft: usually from a pig (porcine) a mechanical valve
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The Need for a Prosthetic Valve Lowell Edwards' interest in working with the mitral valve is thought to have arisen from his childhood battle with rheumatic fever. Despite the decrease in deaths from rheumatic fever from 30/100,000 in 1940 to 12/100,000 in 1958, acute rheumatic fever and chronic rheumatic heart disease continued to be the most common causes of valve failure that necessitated valve replacement. 11,12 The most serious complication of rheumatic fever is valvulitis, the healing of which can lead to thickening, adhesions, and stenosis of the aortic and mitral valves. 13 The heart eventually becomes hypertrophic from the additional force required to pump the blood. 14 For the patient, this means ever-increasing shortness of breath and incapacitation. By the early 1950s, researchers had established the link between streptococcus A and rheumatic fever. The exact mechanisms of the development of rheumatic fever after an infection remain elusive to this day.
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