Early Molecular Genetics

Early Molecular Genetics - Early Molecular Genetics...

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Early Molecular Genetics Correlation Between Chromosomes and Genetic Phenomenon chromosomal behavior in mitosis matches genetic requirements observed events of meiosis are consistent with genetic principles segregation, independent assortment and recombination have chromosomal counterparts Requirements of the Genetic Material contains biological useful information in a stable form must be capable of faithful reproduction and transmission from generation to generation must be capable of occasional change Early Pioneers of Molecular Genetics Garrod-1909 Inborn Errors of Metabolism o catalogued series of diseases that errorred as a result of errors in metabolism (defective enzymes) S. Wright-1917 pigment pathways in guinea pigs o attributed change in coat color to enzymes J.B.S. Haldane-1938, ABO blood system Beadle and Tatum-1941, one gene→one enzyme hypothesis. Experimented with bread mold, haploid organism, and ultraviolet light radiation the hypothesis was
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This note was uploaded on 04/17/2008 for the course BIO 2306 taught by Professor Durhkopf during the Summer '08 term at Baylor.

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Early Molecular Genetics - Early Molecular Genetics...

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