DNA - DNA: The Chemical Nature of the Gene Characteristics...

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DNA: The Chemical Nature of the Gene Characteristics of Genetic Material Genetic Material must contain complex information o genetic material capable of storing large amounts of information o information stored has capacity to vary o genetic material must be stable. Genetic material must replicate faithfully o during cell division genetic instructions must be copied with great accuracy Genetic material must encode phenotype o the genotype must have the capacity to code for the phenotype o gene product is often a protein o translation instructions for the amino acid sequence of a protein is available. Early Studies of DNA In 1869 Miescher discovers nuclein (DNA) in the nuclei of white blood cells by turning his attention to chemistry. o Nuclein was later renamed Nucleic acid In the late 1800s Albrect Kossel determined that DNA has four nitrogenous bases: adenine, cytosine, guanine, and thymine (A, C, G, and T) In early 1900s Phoebus Aaron Levene discovered that DNA consists of a large number of linked repeated units (nucleotides) o each nucleotide contains a sugar, a phosphate, and a base o Introduced the tetranucleotide theory where protein was the genetic
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This note was uploaded on 04/17/2008 for the course BIO 2306 taught by Professor Durhkopf during the Summer '08 term at Baylor.

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DNA - DNA: The Chemical Nature of the Gene Characteristics...

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