summary of a difference in hypothalamic struc.

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Erin LaVanway February 29, 2008 Physiological Psychology Summary Rationale : The rationale of this study was to examine the hypothalamic structure between heterosexual and homosexual men. Objective : The objective of this study was to obtain the role in the size of the interstitial nuclei of the anterior hypothalamus (INAH) on sexual orientation of the subject. Method : Subjects : Nineteen subjects were homosexual men who died of complications of AIDS; sixteen subjects were presumed heterosexual men: six died of AIDS and ten from other causes; six subjects were presumed to be heterosexual women. Apparatus : Brain tissue was obtained from 41 subjects at routine autopsies. Brains were immersed into buffered formalin. Experimental Procedure
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Unformatted text preview: : Sections of the anterior hypothalamus were mounted onto slides and looked at under a compound microscope. The outlines of the four nuclei were traced and compared by size and volume. Drugs : Buffered formalin, 30% sucrose, xylene, 1% thionin in acetate buffer, 5% rosin in 95% alcohol. Results : No differences were found for INAH 1, 2, or 4. INAH 2 was reported larger in men than women. INAH 3 exhibited dimorphism. Conclusion : INAH is dimorphic and suggests that sexual orientation does have a biological substrate. Critique : The differences in the anterior hypothalamus between homosexuals and heterosexuals may be a result of the AIDS virus and not sexual preference....
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