Lecture 6a - LECTURE 6 1 TODAY'S QUIZ AND ANSWER KEYS WILL...

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LECTURE 6 1. TODAY’S QUIZ AND ANSWER KEYS WILL BE POSTED ON OUR WEB SITE TODAY. 2. MEET THIS FRIDAY 9/8 WITH ANY INTERESTED STUDENTS TO DISCUSS, HOW DO I APPLY TO GRADUATE SCHOOL? WHAT ARE THEY LOOKING FOR?! 1:25 - 2:15PM IN COMSTOCK B106. MONDAY’S LECTURE: WHAT ARE THE CONSTRUCTION RULES FOR PROTEIN FOLDING? 1. THE 6 CATEGORIES OF FORCES TODAY: 2. CONSTRAINTS AROUND THE PEPTIDE BOND α -HELIX, β -SHEET, TURNS 3. THE RAMACHANDRAN MAP (ONLY ~15% OF POSSIBLE POLYPEPTIDE CHAIN CONFORMATIONS ARE ALLOWED)
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WHERE WE ARE, WHERE WE ARE GOING IN THE STUDY OF BIOCHEMISTRY: PROTEIN STRUCTURE ENZYME CATALYSIS REGULATION OF ENZYMES BIOMEMBRANES CARBOHYDRATES METABOLISM INTERCONNECTIONS AND CONTROL OF METABOLISM ARE BASED ON PROTEINS WE ARE HERE PROTEINS: WHAT STRUCTURES DO WE OBSERVE? HOW DO CATALYSTS WORK? HOW ARE ENZYMES CONTROLLED? METABOLISM
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SECONDARY STRUCTURE: a-HELIX REPEATING AT LEAST 5 AA: Φ ~ -60 o , Ψ ~ -40 o ALL R GROUPS POINT AWAY FROM HELIX AXIS EVERY PEPTIDE CARBONYL IS ACCEPTOR
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  • Summer '07
  • FEIGENSON,GW
  • STUDY OF BIOCHEMISTRY, POSSIBLE H-BONDS

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