BIBC 120 WI06 Final

BIBC 120 WI06 Final - ASUCSD sOFT RESERVES WINTER 2007...

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Unformatted text preview: ASUCSD sOFT RESERVES WINTER 2007 131130120 E1303 Total: a80¢ ' .—é~ BIBClZO-Final . Name ___)_4_e_§________£/_9_%§I£9_§ _______ 1) (48 pts total, 4 pts each blank) Fill in the blanks: 1) A deficiency of -9i‘itéfl.____ will lead to the disease called pellagra. 2) People who lack the enzyme ‘04)“va . __ have difficulty digesting milk and have the condition called Légizxsr;____ _'\_£\_*S\_€~_<‘&/_\B_«__ (1 word each), which leads to bloating and gas. 3) _£&§5_sa___al~§_§_€£~§_&_______'___ (2 words) is an allergic reaction to gluten. 4) Beriberi is a disease that can be reversed by feeding patients supplements of Mann _____ 5) _l’\i_€£fli‘if\_$ ____________ is a Virus that causes foodborne illness and can be acquired from contaminated shellfish. 6) Food allergies typically result in the production of _l_ E__ antibodies to a specific food allergen. 7) $5132 b93339: _________ (genus name is sufficient) is a bacterium that is the leading cause of foodborne illness in the US. 9) fiflsflfi 02$ ______ is a severe and systemic allergic reaction that can lead to de th. -\ 9* .Qor mivw 5(4Aliyé -5 e) *6)" 0’14st gelling BIBCl 20-Fina1 Name _____ ____ __________________ \ 2) (50 pts) a) (20 pts) Given the structure of beta—carotene below, show the \ structures of retinol and retinal. Retinol: b) (5 pts) What is the RDA for vitamin A for men (in RAE units)? 90 0 My c) (5 pts) What is the RDA for Vitamin A for women (in RAE units)? ”+00% d) (5 pts) What is the Upper Limit for vitamin A for adults (in RAE units)? @«W at 7000*7/ e) (10 pts) What are two major problems or conditions caused by‘vitamin A toxicity? 'H’k M d, “‘7 dfkr Zak) comm liver MW i; b‘ ’ \ (paws. inmfix‘fw's W 6% f) (5 pts) What is the richest food source of Vitamin A (also an organ)? {NJ BIBClZO-Final Name _______________________________ 3) (50 pts). (25 pts) In the TCA cycle, a—ketoglutarate is converted to succinate: a-KGA + NAD+ -> succinate + C02 + NADH. a) Show the structures of the nicotinamide rings of NAD+ and NADH. (+22 My” (onetime!) c+2)NA1>H< MW) 8 H H o / ‘N ”— U0 ”1“?) men/Ya”; \ ' - . 1’ ' ' C-Ho 'Nocw) (”‘40) ' R (+2) ) KHZ) miss &"K" I Wofi 2 POM/("5; “Rh” “Of Wdlfm fi}f0‘l‘l\7f5. m'ssflm owe", fag; afi 3. roofs,- hwwr em , {7M2 Off ' Ffi’d'lf'fead' ' 6w. mew Mum W ,toka off 4%, Cam | Fewt fermgw. b) (25 pts) Thiamin is also needed for this reaction. Show the structure of the thiazOle ring of thiamin attached to the initial reaction intermediate for the above reaction. 0"! 9 ' ° ”Sit—C—CHz’Cf/Z—Zgrf réc N N/Iz. n W“)! ' I , i?“ H \ 27') K _.. g / \c=ca / \R .. .. 0/13 comée “NH 875;“ O ‘ (flak/10‘ ”O I, ‘ - 0/ ID“0 T/momvm sfrudme (+8) <9 0/ e ) 9 oc—KQ’A 3W H8) [ hum/{e Cohuofim (1-3) + efoQ/Foiht 7567‘ QVQ/fyowz . W 0W W. BIBClZO-Final Name _______________________________ 4) (50 pts) Calcium and Phosphorus are two major minerals in bone tissue. a) (15 pts) Would oxalic acid in the diet impede the absorption of both, just one or none of these minerals? Explain. @ OXah'c Wat impede/5 Hug, morph‘ma Mg) at” man] @b/o naval/p wad. b13401: 74b PoJrHUelj Mafia ,ém’ Emsghomy @ PM “a? 02 mflafiv‘e ehoutfle,‘ doom?!— (Mu/1W will/LB /- (pad/c; wad. - b) (10 pts) Calcium homeostasis is very critical because a drop in blood Ca levels can be lethal. Why is this? Give two critical p siological/ cellular functions for Ca besides structural support. {aha/64723 V13 neuron: } Mare 06 WY‘OMHSMFH‘VS flamm (12> mwobes /' gfqmw'p’lj filo mun/115- ’ <~£ormone Vegutahm also 61W .> c) (10 pts) If blood Ca levels drop, the body attempts to restore blood Ca levels. What 2 signals or hormones are produced to increase Ca levels? - fl drawn 0 _ (msmgm «(so acwfiwfiz— @ PMa/‘f’hWI/o/d. “gOVMoVUL. - d) (15 pts) The signals in part c induce three physiological responses that increase Ca levels. What are these 3 physiological responses? Jr; 9 + Cali“ mom'ugcm‘mt W some; is flf 609* rawwgt bi; bangs @729 4‘ 5“” ML ”3 WM <¢ H3 # IOWOVH'on/ aim we? acwffik—L > -BIBC120—Final Name _______________________________ 5) (50 pts) Dietary iron exists in two forms: organic iron (comes primarily from animal—based foods) and mineral iron (found in both animal and plant- based foods). a) (5 pts) What is the name of the organic molecule (not the protein) that binds iron in animal tissues? Hewe,£j 0K Hemogobwiéé) b) (5 pts) Which form of iron is more easily absorbed (organic or mineral)? ‘ O rg cum 0 c) (10 pts) What are the two mineral forms of iron? F€Z+ (or Ferrous) and Fga‘t (or 'FQVHO) d) (5 pts) Which form of mineral iron is more readily taken up by the mucosal cells (brush border) of the intestine? Oink/3 F8“ lg +akem M? 'e) (10 pts)»What is a major barrier in the-lumen of the GI tract for iron absorption? Which form of mineral iron can cross this barrier more easily? MUM/OMS barrier, FGlJrC/VOSSQS more readild f) (5 pts) When mineral iron levels get too high in the blood, they promote the production of what toxic compounds (give generic name)? {1.03, Reactive Oxggeh Sec/ties (0" W0“ COW ' g) (5 pts) What is the name of the protein that stores iron in the intestine? ¥erri+iw h) (5 pts) What is the name of the protein that transports iron from the GI tract to the liver? Jrromsie WI h @ 6 WVLS‘EQ/hfiw BIBClZO-Final Name _______________________________ 6) (52 pts) a) (5 pts) What is the formula for calculating BMI using metric units? i: -2 if 5+“er X706 W /h't2 _. 1 if: WM'i’ $rflo‘3‘m JQMUYCA b) (12 pts) What are the BMI ranges for people for the following classes: normal: 12.5 as (1725-24 4100 0K) ~| H: 12—25 ‘ l—e Ar Om’wufl H overweight: 7.5 ’30 (2; ~25! alga 01's) " "c “Md-W” W" 77-5 Warm»? obese: over 30 -4 4.}, every 8 MI rang/AN "3 c) (15 pts) What are the three major components of energy expenditure? loam membohm ' ‘9?“me ”WW3 an 8 6 fir «Oh : f 14;,Od C4; fian OF) J 'H‘lCYYmc GPO—F ° 3’0 N E RT e) (10 pts) What are two major health risks associated with obesity? can cer oh'qiael—es 3 any 1 5 yit eack cVD (5+1er , NM Whack) f) (10 pts) Give two pieces of evidence that support the claim that . c n ‘ n 1", genetics contributes to obesity. ’2 'l "c ‘Mefikfd' + ,5“ , iden’n'cal 4st reared «PM have, similar BMI: am! a 60%;} rel-es increase an ahnch'an rf fiw huMLeI’ of- obere [>452ng 2 , gauge Madras in mrcaslow 17M sFeq'Hc 8mm can manage oLa‘rU 5 fr; eddy. —2+‘.r every mmlsu’ WW9 (‘ owmngfi) NW murkf . ~BIBC120-Fina1 > Name _______________________________ 7) (50 pts) Joe Adipose does not exercise and is overweight. He decides to go on a no carb diet. He decides to eat only steak and ice cream and drink only whole milk. After two weeks, he notices he has started to lose weight but he is also starting to feel pain around his heart and kidneys. a) (10 pts) Joe’ s diet is not strictly a no carb diet. Which of his three food(s) is/ are Egoviding carbs and what forms are the carbs in? $+1mk —> 9le toJuqu \LO; even ® [email protected] z new a W b) (15 pts) Joe’s doctor runs some tests. What 3 things would the doctor be looking for in his bloo and urine knowing Joe’ s diet and symptoms? . .301; 1‘3 on cx mo low Cum «Md and has hem/t + \ax‘euey vein. 3“?" \NLL$ "HAW—QE‘ M( M LDL G —&Y vufi' sfi‘ (firing: MEMNC may CN warm,” NH?) 1.1..th LEW ku (§3+s we - W9“ [9&ch lavas Lam‘s) M5“ ”Em“ (w15\~{cevxcles)=FAs mum) high (and lupus (\b'N-D ‘ [ow 14+ [JEN/Mg p“, Vszmitw (f8?) 6/: . Pub“ th\£3+tvc\ , [0w 53\“L°3&'\v\5\,\\\m {v ‘Dic—LV; ”d: c) (10 pts) Joe’s doctor recommends that Joe adopt a more Complete diet 6?) with carbs and to take medication. What two general types of medication could the docto rescribe to deal with his weight? ‘ ‘ , < NR \Aszvm ‘AL (evMs when Clm I A file 1A \-L%Sc\’ , 24% Stsofinivt M“ ? ® 0km?\/\s;\-vi iM—l Id?— ® {Eur an“ cmjl W3 (iii/“1&1 (but S +Wt’r \V\\’\\\m+ N059 on 0wa \V\\’\\\/IH“~~F> CWCS 1"“1 ‘QK‘Y )VU)* “Xi-1"“) de ov Bug? d) (5 pts) What IS the most helpful thing Joe could do that is not diet Smi‘wtg {”1" related to help with his lwei ht and overall health? (MW/s Hth c exercise ‘ ELM-HUM hedoi‘rs (+1) e) (10 pts) Give the names of two internal signals that regulate eating behavior and state whether they suppress or enhance the urge to eat. NN‘ WMWULS m QW WW oi sijvut‘ ngc'\"®hC\/\‘- W “\RY‘lSSQ—S ' ~Y s3 Qw $3.301 1'?ch (a C) New mammalim 1 stQ‘RS gar lxshvxj growth]! L—QP‘HVX '_ évqstLSQ—LS é (IO/\d Wig SQWJUS (as?)§ BIBCl 20-Fina1 Name _______________________________ 8) (50 pts) a) (5 pts) Does obesity contribute to cancer risk and diabetes or just diabetes? Barb b) (25 pts) List five- changes that would decrease the risk 0 5K ~§p+s if game progression of colon over 59xqmp'lzg ij O) "‘th i0\\o.\}o\Y\%(5§>t§ ecth/x): r :iibei) \L (Charred)meq+) “\fmcvli and Ueggi'egp Wale loci) SVi+D)\bC~\c©hol)TUthCfl\UlJtPi, J Z +5 {oxf- fifbc 0&4ch — l 3+5 For no+ smwma whaling T/xl/ c) (10 pts) Many cancer studies involve diet intervention where people are told to change their diets (e.g. increase consumption of fruits and vegetables). Surveys are performed to assess how much people change their diets, but these surveys can be inaccurate. Dr. Cheryl Rock discussed a method to get around this problem. What has she incorporated into her studies to determine how much people have changed their diet? _ ° AM of the followiflg (full Wedge). 2 Kim SimdLes -Meoswg& hcfivrtei’fifi in blood - Measfirefig lave?§omqé§~o+gnb\ q\ S W) \O\QQd D 7p+5 1950M) she mode emu Lotus) spend—W ad +8P€S o? fruit-s d) (10 pts) Provide a mechanism for how broccoli might lower cancer risk by briefly stating a beneficial effect on the human body from consuming broccoli at the chemical or cellular level and what stage of cancer development (initiation, promotion or progression and spread) this )3! Ffififihinjég would affect. ° Qflflofldomk ’ \fl‘mbLJrS lhlJr—lOdrléh 0 MPH Prohiemfilpe Otgefli — Lpromoflm/prgamssl&x J/pt‘omOMDW/pm Fesswfl SEES éfibjme occhmksj - qt siqnbes lme ll) Lo\om~ \flvk-‘(xflm iDCMfEd w/ Ouspoflamm WLSYW [69‘ O‘N‘QMQXMWOJ hm 5+0%€/ TU LJV E1 3616mm ...
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