SOQ16_FALL - Study Objective Questions # 16 Cancer Biology...

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Study Objective Questions # 16 Cancer Biology and Cell Technology 1. What are the different mechanisms by which gene transfer takes place? Plasmid creation – excision of a loop of free DNA Conjugation – plasmids transfer from one bacterium to another Transposition – small segments of DNA that are capable of moving from one location to another in the genome, encodes an enzyme called transposase that inserts the transposon into the genome 2. Define mutation. Describe the different types of mutations. Mutation – changes in the hereditary message of an organism Base substitution – pairing errors or polymerase mistakes occur during DNA replication, point mutation bc it involve sone or two nucleotides Chemical modification – base may be chemically altered by a mutagenic chemical, point mutation DNA breaks – ionizing radiation can cause double-strand breaks in DNA, results in deletion or loss of short segments Slipped mispairing – like buttoning a shirt wrong, produces a short
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SOQ16_FALL - Study Objective Questions # 16 Cancer Biology...

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