Lecture 4a - LECTURE 4 ANNOUNCEMENTS: 1. QUIZ 1 WILL COVER...

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LECTURE 4 1. QUIZ 1 WILL COVER THE FIRST 3 LECTURES (AMINO ACIDS AND PEPTIDES), PLUS THE RASMOL TUTORIAL. MORE INFO ON MONDAY. ANNOUNCEMENTS: 2. USE THE VOH! SEND MAIL TO BIO331@CORNELL.EDU 3. MONDAY 9/4: NEW TO CORNELL? YES, WE DO HAVE CLASS ON LABOR DAY 4. ANY INTERESTED STUDENTS: “HOW TO FIND A LAB RESEARCH POSITION. WHAT ARE THEY LOOKING FOR?!", 1:25 - 2:15PM, TODAY IN COMSTOCK B106. WEDNESDAY’S LECTURE: IONIZABLE GROUPS THE HYDROPHOBIC EFFECT 5. ENROLLMENT IN THIS CLASS:STARTING TODAY, MUST GET MY PERMISSION TODAY: 1. WHAT CAN WE SAY ABOUT PROTEINS WITHOUT KNOWING THE 3D STRUCTURE? INTRO TO MYOGLOBIN PEPTIDES PROTEIN 3D STRUCTURE 2. FINDING THE 3D STRUCTURE 6. STUDENT DOCTORS ORGANIZATION-- FIRST MEETING TH 9/7 ISOZYMES 7. BIOLOGY CENTER OPEN HOUSE TU 9/5 Tuesday, September 5th 4:00 - 5:30 PM 216 Stimson Meet Faculty, Drink “Mocktails,” Eat Pizza, Learn About Biology
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WHAT TO DO WITH AA SEQ: NO 3D STRUCTURE YET! 1. a. FUNCTION: ENZYME ACTIVITY b. FUNCTION: BINDING DOMAINS ~ 4 MILLION PROTEIN AA SEQUENCES NOW KNOWN! KEY TO INTERPRETATION: FIND RELATEDNESS TO ALREADY KNOWN PROTEINS. CURRENT SOFTWARE + INFORMATION TECHNOLOGY: FIND MATCHES FOR ~50% EXAMPLE: ~ 35 YEARS AGO, GENES AND PROTEIN PRODUCTS OF THOSE GENES FOUND ASSOCIATED WITH CANCERS. ROLE OF THESE PROTEINS (FUNCTION INSIDE CELLS)?!
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Lecture 4a - LECTURE 4 ANNOUNCEMENTS: 1. QUIZ 1 WILL COVER...

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