37 - ANNOUNCEMENTS LECTURE 37 1 READING 787-798 804-829...

Info icon This preview shows pages 1–4. Sign up to view the full content.

LECTURE 37 ANNOUNCEMENTS 1. READING 787-798 & 804-829; PROBLEMS AS IN LG FOR THIS WEEK. 2. “MAKE-UP QUIZ” WED 11/28. COVERS LECTURES 11/12, 11/14, 11/16, AND TODAY. TURN IN THE MAKE-UP QUIZ ONLY IF FEWER THAN 9 QUIZZES HAVE BEEN PREVIOUSLY TAKEN . YOU MIGHT HAVE MISSED ONE OF THOSE 9 QUIZZES FOR ANY REASON-- THE REASON IS NOT IMPORTANT. 3. MUST LET PROF KNOW ABOUT FINAL EXAM CONFLICT BEFORE NOON ON WED 11/28. 4. NO CLASS ON WED 11/21 FRIDAY’S LECTURE 1. CALVIN CYCLE: 3 STAGES, (i) FIX CO 2 ; (ii) SYN SUGAR; (iii) REGENERATE Ru-1,5-BP TODAY BIOSYN OF FAT AND PHOSPHOLIPID THE CHOLESTEROL STORY 2. FA BIOSYN: (i) ROLE OF MALONYL-CoA; (ii) FA SYNTHASE ENZ: CHANNELLING FA BIOSYN; LOCAL AND HORMONAL CONTROL 5. NO OFFICE HOURS OR REVIEW SESSIONS THIS WEEK GLUCONEOGENESIS MAIN SITE IS THE LIVER MAIN STARTING MOLECULES: LACTATE AND ALA "BYPASS" OF ONLY 3 STEPS OF GLYCOLYSIS MAIN REGULATION: PYRUVATE CARBOXYLASE REQUIRES ACETYL-CoA 6. REVIEWS/OFFICE HRS FOR STUDY WEEK ARE NOW POSTED ON BLACKBOARD. EACH REVIEW COVERS ENTIRE COURSE.
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

LONG, FLEXIBLE ARM OF ACYL CARRIER PROTEIN (ACP) 7 DIFFERENT ACTIVE SITE S PRODUCTS STAY BOUND UNTIL LAST STEP: CHANNELING ANIMALS: 1 POLYPEPTIDE WITH 7 ACTIVE SITES BINDING STEPS. NO RXN YET FATTY ACID SYNTHASE 8 ACETYL-CoA + 7 MALONYL-CoA + 14 NADPH + 20 H + PALMITIC ACID + 7 CO2 + 14 NADP + + 7H 2 O + 8 CoA ON THIS PAGE: WEIRD DIAGRAM, SHOWING INTERMEDIATES “IN SPACE”-- REALLY, IN ACTIVE SITES OF ENZYMES!! BACT., PLANTS: 7 DIFF POLYPEP .
Image of page 2
FATTY ACID SYNTHESIS NOTES ELONGATION: e.g. 16:0 18:0 20:0 etc " ENZYME: 9 UNSATURATION: e.g. 16:0 16:1 or 18:0 18:1 9 ENZYME: MAMMALS CANNOT ADD UNSATURATION BETWEEN AND TERMINAL METHYL!
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Image of page 4
This is the end of the preview. Sign up to access the rest of the document.
  • Summer '07
  • FEIGENSON,GW
  • Atherosclerosis, Fatty acid metabolism

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern