Lecture 5a - ANNOUNCEMENTS: 1. QUIZ WED 9/6. MORE INFO AT...

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ANNOUNCEMENTS: 1. QUIZ WED 9/6. MORE INFO AT THE END OF TODAY'S LECTURE. FRIDAY'S LECTURE WHAT TO LEARN FROM AA SEQ WITHOUT 3D STRUCTURE: UNKNOWN PROTEIN-- LOOK FOR AA SEQ MATCH WITH KNOWN PROTEINS FIND EVOLUTIONARY RELATIONSHIPS TRY TO PREDICT 3D STRUCTURE(!) 3D STRUCTURE: X-RAY DIFFRACTION INTRO TODAY'S LECTURE WHAT ARE THE "RULES" FOR PROTEIN STRUCTURE? 5. REVIEW SESSION IN ROCKEFELLER TODAY AT 5:30 PM AND TU AT 3:15PM. 3. OFFICE HOURS: TODAY: 2 - 4PM IN BIOTECH 202 TUESDAY: 9AM - 3PM IN BIOTECH 202; RASMOL IN BIOTECH G01 FROM 4:30 - 5:30PM 2. READING & PROBLEMS FOR THIS WEEK: AS IN LG FOR 9/4, 9/6, & 9/8 4. LECTURE REVIEW, BIOTECH G01 FROM 4 - 5PM TODAY 6. PC USERS: SEE THE BLACKBOARD ANNOUNCEMENTS FOR RASMOL HELP FILES MAC OS 10.4 USERS: NO FIX TO RUN RASMOL! RUN RASMOL IN WINDOWS OS BOTH MAC & PC USERS: DOWNLOAD NEW INSTRUCTIONS FOR RASMOL #2 7. SUNDAY 1 - 3PM RASMOL REVIEW: NOW MOVED TO CARPENTER RED ROOM!
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FROM THE CHRONICLE ONLINE (THANKS, NASIM!)
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6 CATEGORIES OF FORCES or, WHY DO PROTEINS HAVE STRUCTURE?! 1. HYDROGEN BONDS 2. ELECTROSTATIC 3. DISULFIDE BOND 10 - 40 kJ/MOLE EVERY OH, SH, NH IS H-BONDED TO (1) ANOTHER PART OF PROTEIN; OR (2) WATER THE PROTEIN STRUCTURE-- WHATEVER IT IS-- MUST ALLOW ~ EVERY POSSIBLE H-BOND TO FORM 10 - 40 kJ/MOLE ON PROTEIN SURFACE, THIS REQUIREMENT MET BY AQUEOUS SALT IONS.
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Lecture 5a - ANNOUNCEMENTS: 1. QUIZ WED 9/6. MORE INFO AT...

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