Gene_expression

Gene_expression - Biology 111 Principles of Biology Lecture...

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Biology 111, Principles of Biology Lecture Outlines Gene Expression Gene Expression: production of a functional product from a gene. Usually a PROTEIN May be an RNA molecule Production of a protein product requires the completion of two distinct processes (see Figure 17.3): Transcription: Synthesis of an RNA copy from a DNA template Translation: Synthesis of a polypeptide from a mRNA template Overview of Gene Expression (see Figure 17.4): Transcription: Sequence of bases in DNA are copied into a complementary sequence of RNA Overview of transcription of a gene (see Figure 17.7): Requires the enzyme RNA Polymerase Start at a PROMOTER Synthesis in 5’ 3’ direction (just like DNA polymerase) Ribose in RNA instead of deoxyribose (as in DNA) Uracil in RNA instead of thymine (pyrimidines) Transcription stops at a specific TERMINATOR sequence in prokaryotes Usually only ONE strand of a segment of DNA (gene) is transcribed into RNA (see Figure 17.7b): Three major types of RNA are produced: 1. mRNA: messenger RNA, encode proteins, will be translated in the cytoplasm.
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Gene_expression - Biology 111 Principles of Biology Lecture...

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