fungalpath - from Fernandez-Canon JM and Penalva MA (1995)...

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Phenylalanine Tyrosine 4-hydroxyphenylpyruvate Homogentisate Maleylacetoacetate Fumarylacetoacetate Fumarate + Acetoacetate 4-hydroxyphenyacetate Phenylacetate Additional Pathway in Aspergillus Homogentisic Acid Oxidase Fumarylacetoacetic Acid Hydrolase Northern Blot for Fungal Fumarylacetoacetic Acid Hydrolase Human and Fungal Phenylalanine Degradation AKU HT1 HT1 = Type I Hereditary Tyrosinemia
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Unformatted text preview: from Fernandez-Canon JM and Penalva MA (1995) Fungal metabolic model for human type I hereditary tyrosinaemia. Proc Natl Acad Sci USA 92:9132-6. Note that inhibiting 4-hydroxypenylpyruvate dioxygenase with a drug is clinically useful for HT1 (Lindstedt et al. 1992, Lancet 340: 813-7) 4-OH phenylpyruvic acid dioxygenase *...
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This note was uploaded on 04/17/2008 for the course PCB 3063 taught by Professor Marta during the Spring '08 term at University of Florida.

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