PSYC132-4-09-08-AbusiveDrugs - increases availability of...

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Sheet1 Page 1 PSYC 132, 4/09/08 ABUSIVE DRUGS Top five drugs of abuse: 1) Nicotine (stimulant found in tobacco) --an acetycholine agonist binds to nicotine receptors found in central nervous system & PNS --endogenous neurotransmitter for nicotine receptor is acetycholine 2) Alcohol (depressant) --enhances effect of GABA at GABA receptors neurotransmitters (eg: dopamine) --areas of brain that are especially vulnerable to chronic alcohol-related damage are the cerebral cortex, the hippocampus, and the cerebellum 3) Marijuana (hallucinogenic) --active ingredient is THC --acts at endogenous cannabinoid receptors --marijuana is the most commonly abused illicit substance coordination 4) Cocaine (short-acting stimulant) --can lead users to binge --increases the release and blocks reuptake of dopamine molecules reuptake: refers to re-uptake and re-use of neurotransmitter by neurons
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Unformatted text preview: increases availability of neurotransmitter to bind to receptor. Most antidepressants are serotonin reuptake inhibitors, which increase availability of serotonin 5) Amphetamines (stimulants that produce feelings of alertness/euphoria)--examples are meth, ritalin--many amphetamines increase the release and activity of dopamine/norepinephrine neurons makes us focused and/or hyperactive AGONISTS: these mimic neurotransmitters BLOCK RECEPTORS: drug molecules that block receptor and prevent neurotransmitter from acting on receptor Almost all psychoactive drugs by modulating synaptic transmitter. ..-mimic neurotransmitter-block endogenous neurotransmitter-increase release of neurotransmitter Sheet1 Page 2 indirectly increases release of a number of can impair memory, attention, and blocking reuptake this...
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This note was uploaded on 04/12/2008 for the course PSYC 132 taught by Professor Chrobak during the Spring '08 term at UConn.

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PSYC132-4-09-08-AbusiveDrugs - increases availability of...

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