A&P 1 md 3 slides .pdf - 7/3/2021 Bone Tissue Anatomy and...

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7/3/20211Bone TissueAnatomy and Physiology IObjectivesIdentify the anatomy of bone tissueCompare and contrast the bone cellsIdentify the anatomy and explain the role of thecomponents within extracellular space of bone tissueCompare and contrast the characteristics andanatomical structures of spongy and compact bone7/3/20212Bone Tissue:Overview7/3/20213Bone tissue is composed ofbone cells and extracellularmatrixOsteogenic, Osteocytes,Osteoblasts, OsteoclastsClassified as either spongy orcompact boneBoth have the same bone cells andmatrix but it’s arranged differentlySpongyCompact123
7/3/20212Bone Tissue: CellsOsteogenic CellsStem cells that give rise to other bone cells• OsteocytesFormer osteoblasts that become trapped in matrix theydepositedLacunae- tiny cavities that they reside inCanaliculi- narrow channels that connect the lacunae7/3/20214Bone Tissue: Cells• OsteoblastsBone matrix forming cellsSynthesize soft organic matter of the bone matrixHardens by mineral depositStress and fractures stimulate production of these cells• OsteoclastsBone matrix dissolving cells found on the bone surfaceRelease minerals (calcium) into bloodstream7/3/20215Bone Tissue: Cells7/3/20216456
7/3/20213Bone Tissue: Extracellular MatrixComposed of Organic and Inorganic matterSurrounds the bone cellsDry weight of bone:1/3 organic2/3 inorganicTogether form a very strong but slightly flexible bone7/3/20217Bone Tissue: Extracellular MatrixOrganic MatterSynthesized by the osteoblastsIncludes collagen fibers and other protein basedcomplexesStimulates the incorporation of calcium into the bonematrixInorganic Matter85% Hydroxyapatite (calcium – phosphate salt)10% calcium carbonate5% random ionsOsteoclasts “break down” the mineral salts7/3/20218Compact Bone and Spongy BoneBoth contain the four categories of bone cellsBoth contain the same extracellular matrixDifference is that the extracellular matrix is arrangeddifferently7/3/20219789
7/3/20214Compact BoneArranged in structures called OSTEONSEach osteon has:Central (Haversian) canalBlood vessels and nerves run throughConnected together by perforating (Volkmann) canalsConcentric rings of calcified matrix called lamellaeOsteocytes are found in lacuna which are connectedto other lacuna through canaliculi7/3/202110Compact Bone7/3/202111OsteonSpongy BoneArranged in structures called TRABECULAEOsteocytes and the lacuna which are still connected toother lacuna through canaliculi

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