Exam01_FA07_KEY

Exam01_FA07_KEY - EXAM #1 (100 points) BC 351 Fall 2007...

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Unformatted text preview: EXAM #1 (100 points) BC 351 Fall 2007 Some Potentially Useful Information: Amino Acid pK 1 -COOH pK 2 -amino pK R side chain gly 2.34 9.60-- ser 2.21 9.15 13.6 glu 2.19 9.67 4.25 asp 1.88 9.60 3.65 lys 2.18 8.95 10.53 arg 2.17 9.04 12.48 his 1.82 9.17 6.00 val 2.32 9.62-- pro 1.99 10.96-- G=H-TS G = -RTlnK eq Answer Sheet instructions: Fill out your name and your Student ID# which is NOT your SSN. Hand the bubble sheet in a stack that I designated up front. The test and the short answer section must be handed in separately and I have given instructions for this on the short answer sheet. Matching Instructions-Fill in the correct bubble for the BEST answer to each of the following: There is only one correct answer per question. Each question is worth 4.0 points. Set One (Question # 1-5 on your answer sheet) 1. _D_ Ligand A. Cannot be changed by an enzyme. 2. _E_ Substrate B. A constant directly related to the change in free energy of a chemical reaction. 3. _C_ Activation energy C. Energy required to reach the transition state. 4. _B_ K eq D. Any molecule that binds a protein. 5. _A_ Change in Gibbs energy E. Any molecule that binds the active site of an enzyme. Set Two (Question # 6-10 on your answer sheet) 6. _C_ Cooperative binding A. Negative modulator of hemoglobin. 7. _D_ Allosteric Protein B. Concentration of substrate required to meet of V max . 8. _A_ BPG C. Binding of one ligand affects the binding of another ligand. 9. _B_ K m D. Hemoglobin is an example of one of these. 10. _E_ K d E. A measure of affinity of a protein for its ligand. Multiple choice Instructions-Fill in the correct bubble for the BEST answer to each of the following: There is only one correct answer per question. Each question is worth 3 points. 11. The bond dissociation energy for an ionic bond in sodium chloride: A) increases when sodium chloride is transferred from a polar to a non-polar solution due to an increase in the distance between the two ions (Na + and Cl- ). B) decreases when sodium chloride is transferred from a polar to a non-polar solution due to an increase in the distance between the two ions (Na + and Cl- ). C) increases when sodium chloride is transferred from a polar to a non-polar solution due to solvent effects. D) decreases when sodium chloride is transferred from a polar to a non-polar solution due to solvent effects. E) None of the above are correct and therefore E is my best choice....
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Exam01_FA07_KEY - EXAM #1 (100 points) BC 351 Fall 2007...

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