{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

02/05/08 Lecture Notes

02/05/08 Lecture Notes - Tuesday February 5th Types of...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Tuesday, February 5 th Types of Neuron Communication 1. Electrical- action potentials 2. Chemical- synapses, neurotransmitters Identifying Neurotransmitters: - had to block them to discover them - if body responds to a drug, it means that something that naturally occurs that is similar is being disrupted Recall: How to stop a signal from firing: 1. Reuptake 2. Enzyme deactivation 3. Autoreception Basic Neurotransmitters (close to 100 are identified & well understood) 1. Dopamine a. Function i. Reward, positive feelings, motivation, voluntary movement b. Malfunction i. No dopamine = Parkinson’s disease (how we know about movement part because w/ Parkinson’s, you get tremors ii. Too much dopamine (meth, others) 1. Low doses- euphoria, wakefulness, activity, decreased appetite, confidence, physical stimulation 2. High Doses- intense pleasure, irritability, insomnia, confusion, hallucinations, anxiety, paranoia, increased aggression 3. Higher Doses- hypothermia, convulsions, death c. Drugs i. In almost every recreational drug (not necessarily primary one) ii. Crystal Meth- an agonist- too much dopamine iii. Stem cells can be good producers of dopamine 1. why Parkinson’s people want stem cell research iv. Cocaine/Amphetamines 1. blocks reuptake. Prevents reabsorption 2. dopamine builds up and continues to stimulate receptor. 2. Acetylcholine a. Function i. Messages about muscle movement ii. Learning, memory, sleeping, dreaming b. Malfunction i. Alzheimer’s- ACh producing neurons deteriorate c. Drugs i. Curare- blocks ACh receptors 1. south African darts 2. surgery
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
ii. Botulism 1. in food 2. inhibits release of n’transmitters iii. Nicotine 1. makes you jittery, people that smoke only when drinking to enhance the effect 2. increases short term memory recall 3. nicotine patch users report having vivid dreams 3. Norepinepherine a. Function i. Eating, alertness, arousal- excitatory ii. States of focused attention iii. Released from Locus Coeruleus 1. sensitive to light- tells you to wake up 2. goes to hypothalamus b. Malfunction i. Undersupply can depress mood ii. Decreased in people with depression (dopamine, serotonin too) c. Drugs i. For depression, certain drugs only target one specific n’transmitter, so it is necessary to try more than one to find what works 4.
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 5

02/05/08 Lecture Notes - Tuesday February 5th Types of...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon bookmark
Ask a homework question - tutors are online