Chapter 16-2 notes - THERAPIES CHAPTER 16(continued...

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THERAPIES CHAPTER 16 (continued) Antidepressant Drugs *Prescribed for _______________ mainly *_______ antidepressants also are prescribed for ______ __________ ____________ and __________ ____________ *Several types of antidepressants o _____________ o MAOIs o Various ________ antidepressants Tricyclics *Elavil, Sinequan, Anafranil, Tofranil *Block reuptake of norepinephrine & serotonin molecules into the axon terminals, increasing the activity of these chemicals in the synapses *Powerful – can have unpleasant side effects Monoamine Oxidase Inhibitors *Nardil, Parnate, Marplan *Block the action of an enzyme (monoamine oxidase) that breaks down monoamines like norepinephrine & serotonin in the synapses increasing the activity of these chemicals *Can have unpleasant side effects *Interact with many other medications, including over-the-counter drugs & some foods Newer Antidepressants *Selective serotonin reutake inhibitors (SSRI’s) – Prozac, Zoloft, Paxil, Lexapro, Celexa *Block the reuptake of serotonin, increasing its activity in the synapses *Have fewer side effects & are safer in overdoes than lprevious antidepressants *Can be effective in treating OCD, social phobia, & panic disorder *Various other new ones – Wellbutrin, Effexor, Desyrel, Cymbalta *Act in various ways (may block reuptake of norepinephrine, for instance)
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Lithium & Anticonvulsants *Lithium cabonate – Eskalith, Lithobid, Lithonate *Used in bipolar disorder to control the symptoms in a manic episode & to even out the mood swings *Reduce recurrence of future manic & depressive states *“Wonder drug” for 40-50% of bipolar patients *Overdose is dangerous *Anticonvulsants (antiseizure drugs) – Depakote, Tegretol *Recent research suggests these may be just as effective as lithium for managing
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  • Spring '08
  • Mason-Hall
  • Antidepressant, cognitive therapies, monoamine oxidase inhibitors, Tofranil *Block reuptake, serotonin reutake inhibitors, O. C. Therapies

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