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second midterm 064 - BIOL300 Second Midterm Exam Fall 2006...

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BIOL300 Second Midterm Exam Fall 2006 Nov. 13, 2006 Instructor: Mike Chao Name:______________________________ Student ID:_________________________ 1
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Part A. True/false questions (7 points each, 70 points total) Write "T" or "F" in the space provided to indicate true or false, respectively. If you answer false, be sure to correct the statement to make it true for full credit. ( ) 1. Lipid bilayers made up of phospholipids with unsaturated hydrocarbon tails (i.e., tails with cis -double bonds) are more fluid than lipid bilayers made up of phospholipids with saturated hydrocarbon tails. ( ) 2. The ribosome is made up of both RNA and protein, but RNA is used to catalyze peptide bond formation. ( ) 3. The protein translocation channel (also called Sec61) is located on the smooth ER. ( ) 4. Channels that carry out passive transport must couple to an energetically favorable reaction such as Na + transport or ATP hydrolysis. ( ) 5. The amplitude of an action potential depends on the strength of the depolarizing stimulus: the stronger the stimulus, the larger the action potential. ( ) 6. Voltage-gated Na + channels and K + leak channels both contribute to the amplitude of the action potential. ( ) 7. Microtubule polymerization depends on both the concentration of unpolymerized α-β tubulin heterodimer and the concentration of microtubule polymer. ( ) 8. During mitosis, kinesins (which are plus end motor proteins) as well as dyneins (which are minus end motor proteins) are important for the function of the mitotic spindle. ( ) 9. Translation is terminated by a terminator tRNA. ( ) 10. Calnexin is an enzyme in the ER that degrades misfolded proteins. 2
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Part B. Multiple choice (7 points each, 70 points total) . Clearly write your answer in the space provided. Do not circle or draw checkmarks next to your answer! Make sure you read the entire question and selection choices before answering! (
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