midterm exam 2 BIOL300 Fall 05

midterm exam 2 BIOL300 Fall 05 - STUDENT NAME:_ STUDENT...

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STUDENT NAME:________________________ STUDENT ID#:___________________________ COVER PAGE Fall 2005 BIOL300 Cell Physiology Second Midterm Exam Lectures 11-18 November 7, 2005 Instructor: Mike Chao STUDENT NAME:______________________________ STUDENT ID#:_________________________________ DO NOT TURN TO PAGE 2 UNTIL INSTRUCTED TO DO SO 10 true/false questions: 3 points each 15 multiple choice questions: 3 points each 5 fill in the blank questions: 4 points each 3 essay questions: 10 points each 1 bonus question: 10 points total: 125 points (yes, it's right this time) 1
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STUDENT NAME:________________________ STUDENT ID#:___________________________ This area for instructor use only: Scantron results: Essay questions: Bonus question: Total: Part A. True false questions: 10 questions, 30 points, 3 points each. On your Scantron forms, mark "A" for true and "B" for false. 1. Transport of small molecules against a concentration gradient requires a transporter that in effect acts as a pump. This pump does not necessarily directly utilize ATP, because it can couple to other energy sources. 2. Cells utilize a Na + /K + ATPase to generate a Na + gradient. The end result is that Na + concentrations are higher inside the cell than outside the cell, and vice versa for K + . 3. The "search and capture" mechanism of kinetochores by microtubules is based upon a basic principle of microtubule dynamics, namely treadmilling. 4. The electrochemical gradients of both Na + and K + are major contributors to the resting membrane potential in a typical eukaryotic cell. 5. All proteins in the cell are synthesized on the rough ER and are distributed throughout the cell via vesicle transport. This includes both soluble and transmembrane proteins. 6. N-linked glycosylation plays an important role in protein folding quality control in the Golgi. 7. The basic unit of microtubule formation is the α - β tubulin heterodimer. 8. Small GTPases, such as Rab (involved in vesicle docking) and Sar1 (involved in recruitment of vesicle coat proteins) are like molecular switches. They are active in the GTP bound state, and inactive in the GDP bound state. 9. The stronger the input to a neuron is, the more depolarized the axonal membrane becomes during an action potential. 10. M-cyclin dependent kinase (M-Cdk) is a key regulator of entry into M-phase during the cell cycle. 2
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STUDENT NAME:________________________ STUDENT ID#:___________________________ Part B. Multiple choice: 15 questions, 45 points, 3 points each. Answer on your Scantron form. 11. Which of the following is NOT a general property of carrier proteins? (a) They are transmembrane proteins. (b) Depending on the particular carrier protein, they can transport small molecules up or down a concentration gradient. (c) They form a contiguous hydrophilic pore that spans the membrane, thus allowing
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midterm exam 2 BIOL300 Fall 05 - STUDENT NAME:_ STUDENT...

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