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BIOL300 074 second midterm - BIOL300 Cell Physiology Fall...

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BIOL300 Cell Physiology Fall 2007 Second Midterm Exam Nov. 9, 2007 9:20-10:30 AM CS-128 Instructor: Mike Chao, Ph.D. Name: _________________________________ MyCoyote Number:__________________________
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Part A. True/false questions (8 points each, 80 points total): ( ) 1. mRNAs already have proteins bound to them even before they are exported out of the nucleus. ( ) 2. Since there are 20 different amino acids and 2 4 =64 different possible combinations of triplet nucleotides in a triplet genetic code, different codons can code for the same amino acid. ( ) 3. Glycosylation of proteins occurs only on proteins that have extracellular domains. ( ) 4. Signal peptides bind to signal recognition particles (SRPs). In turn, SRPs bind to SRP receptors on the rough ER. ( ) 5. Misfolded proteins in the rough ER are exported from the ER lumen, tagged by ubiquitin, and degraded in the cytoplasm by the proteosome. ( ) 6. Depending on the intracellular and extracellular concentrations of K + , the Na + / K + ATPase can move K + either in or out of the cell. ( ) 7. Depending on the intracellular and extracellular concentrations of K + , K + channels can move K + either in or out of the cell. ( ) 8. Action potentials originate in the dendrites of neurons. ( ) 9. An excitatory post-synaptic potential (EPSP) is "all-or-none". ( ) 10. The resting potential is caused by K + channels opening and closing, leading to movement of K + ions across the membrane. 2
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Part B. Multiple choice questions (10 points each, 100 points total) Do not circle your answers. Write your answer between the parentheses. ( ) 11. How does a specific amino acid become attached to a specific tRNA? (a) The amino acid attaches to the tRNA through specific Watson-Crick base pairing. (b) The amino acid and the tRNA both bind to a specific aminoacyl transferase and become covalently linked. (c) The amino acid and the tRNA both bind to ribosomes and become covalently linked. (d) This is a lie. Amino acids do not attach to tRNAs. (e) None of the above.
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