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REVIEW MODULE CHAPTER 31
CATEGORY CLASS Thiazide diuretic, diuretic
PURPOSE OF MEDICATION
Expected Pharmacological Action
Adjunct therapy for edema associated with Ill, cirrhosis,
inhibbits the reabbsorption of sodium and
corticosteroid or estrogen therapy, and renal dysfunctionn;
Irealment of hypertension as monotherapy or in combination
chloride in distal renal tubules, increasing the
with ollen antihypertensives
excretion of sodium, chloride, and water by
Hypersensitivity, dizziness, vertigo, orthostatic
Adult: 25-100 mg/d intermediately. up
hypotension, nausea, anorexia, vomiting, dry mouth,
to 200 mg/d maximum for edema;
diarrhea, polyurea, nocturea, muscle cramps, or spasms.
25-100 mg/d for hypertension
Pediatric (<6mo): up to 3mg/kg/d PO
n 2 divided doses
Pediatric (6mo-2y):12.5-37.5 mg/d in 2
Pediatric (2-12y): 37.6-100 mg/d PO in
2 divided doses
Anurea, hypersensitivity, other thiazides, sulfonamide
derivatives or their components.
Monitor glucose levels.
Assess BP regularly.
Have pt dangle feet before
arising from bed
Monitor for fluid/electrolyte
ACTH, corticosteroids, amantadine, amiodarone,
antihypertensives, barbituates, calocium, carbamazepine,
cholestyramine, cyclosporine, digoxin, insulin, lithium,
NSAIDs, oral anticoagulants.
Take early moming/early evening to
Evaluation of Medication Effectiveness
Take with good if GI upset.
Weigh at same time each day, with
Pt has blood glucose WNL
Pt ability to urinate in tact.
Diet rich in potassium.
Pt weight does not increase.
Teach about ortho hypotension.
BP remains WNL.
Seek Dr. if muscle cramps, weakness,
No fluid/electrolyte imbalance
unusual bleeding or bruising-...
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