Chapter 10 Part II - Muscle Metabolism ATP for contraction...

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ATP for contraction comes from: Creatine phosphate Anaerobic glycolysis Cellular respiration Muscle Metabolism
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Production of ATP in Skeletal Muscle
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Energy Sources and Fatigue Interactions Animation: Muscle Metabolism Role of ATP in Muscle Movement and Fatigue You must be connected to the Internet and in Slideshow Mode to run this animation.
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The inability to maintain force of contraction after prolonged activity Due to: Inadequate release of Ca 2+ from SR Depletion of CP, oxygen, and nutrients Build up of lactic acid and ADP Insufficient release of ACh at NMJ Not the same as central fatigue – CNS changes “wanting to quit” Muscle Fatigue
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Oxygen debt - breathing heavily for a period of time after stopping exercise Oxygen debt Replenish CP stores Convert lactate into pyruvate Reload O 2 onto myoglobin which stores O 2 in the SR Oxygen Consumption After Exercise
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A motor unit consists of a somatic motor neuron and the muscle fibers it innervates The strength of a contraction depends on how many motor units are activated Control of Muscle Tension
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