Exam 1 Study Guide


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NEW YORK UNIVERSITY - CENTER FOR NEURAL SCIENCE V23/V80.0100 - Introduction to Neural Science Sample Examination Questions, 27 September 2007 (Lectures 1-7) I assume you will have reviewed the questions at the end of each assigned chapter in the Bear et al. textbook. They are all relevant for the exam. I provide below examples of questions that may be asked on the material covered in the first seven lectures. Some exam questions will be based on these sample questions, which include my own questions as well as some taken from Bear et al . Others will be based on different end chapter questions in Bear et al. ; and still others will be new. 1. Compare and contrast anterograde and retrograde axonal transport. In anterograde transport, vesicles walked down the microtubules of the axon by ‘legs’ which are provided by a protein called kinesin and fueled by ATP. Kinesin only moves material fromo somoa to the terminal. Retrograde transport is believed to provide signals to the soma about changes in the metabolic needs of the axon terminal. The legs for retrograde transport area provded by dynein. 2. Compare and contrast axosomatic, axodendritic and axoaxonic synapses. Discuss the structure and function of each type. Axosomatic, inhibitory; axodendritic usually excitatory, axoaxonic is both 3. Discuss the methods used by Hodgkin and Huxley to establish the ionic basis of the action potential in the squid giant axon. 4. Name three factors responsible for causing ions to cross the resting cell membrane, and indicate whether each is an active or passive process. 1) Diffusion – when ions move from a region of high concentration to a region of low concentration until an equilibrium is reached. 3 Na out and 2 Ka helps establish concentration gradient 2) Electricity - ions move since they are electrically charged particles and a net movement of + ions (K+) to negative terminal while – ions (Anions) to the positive terminal 5. What is the neuron doctrine ? What is its significance for the contemporary understanding of information processing in the nervous system? Cajal followed all laws of of cells. Golgi believed in a nerve net where the nervous system was one basic unit. Cajal was right when it was proven that neurons weren’t connected but communicated with one another. This is important because it is the basic idea of neurons communicating with each to send signals to and from the brain. 6. What is the
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This note was uploaded on 04/17/2008 for the course NEURO 101 taught by Professor Mosh. during the Fall '08 term at NYU.

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