1Genetics and the Life Span•Why is genetics important to life-span development?Genetic Foundations•What is the difference between phenotype and genotype? •Whether or not a particular characteristic is expressed is often determined by our genotype (Dominant-Recessive Inheritance)•Ex: Curly Hair, Facial DimplesGenetic Material and Processes• Material: – Chromosomes•23 pairs (22 pair autosomes, 1 pair sex) – Gene• Alleles•Homozygous vs. Heterozygous– Deoxyribonucleic acid (DNA)• Processes:– Mitosis– Meiosis• Gametes• Zygote
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2Dominant-Recessive Inheritance•The dominant allele determines phenotype, whereas the recessive allele does not affect phenotype. However, if have 2 recessive alleles, that genotype will be expressed.VERY FEW diseases that have a dominant inheritance. Why? Ex: Huntington DiseaseEx: Phenylketonuria(PKU), Curly Hair, Facial Dimples, Type A vs. Type OKeep in Mind: Parent can be carriers (heterozygous)X-Linked Inheritance•Phenotypes related to traits