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FtsZ Protein in E

FtsZ Protein in E - FtsZ Protein in E Coli Z Ring Formation...

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FtsZ Protein in E. Coli Z Ring Formation and Cell Division By Katrina Gumina
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FtsZ Basics Cytosolic GTP-ase Cell division protein Polymerizes into filaments that form cytoskeleton-assembles Z-Ring Action is key step in commitment to cell division Recruits other cell division proteins GTP-domain homologous to Tubulin
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Why Study FtsZ? Homology with tubulin and lead role in cell division Discover the mechanism of FtsZ in cell division Get better understanding of eukaroytic cell division
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Looked at Research Conducted to investigate: FtsZ protein’s role in the assemblage of Z- Ring Factors that influence and affect ftsZ ring formation Some of the proteins that interact with ftsZ protein and the Z-Ring
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Role in Z-Ring Formation Migrates to midcell FtsZ mutants fail to form functional Z-ring (or no Z ring at all) Rate-limiting step dependent on [ftsZ] Septation follows formation and z-ring contracts FtsZ dissembles How cell division site determined and what constitutes site is unknown
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