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A+PII Lab 2 - 47.16 26.74 145.57 0.4 49.54 56.28 190.18...

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10/31/07 Anatomy and Physiology II Studying the Effect of Pressure on Glomerular Filtration Objective : To determine the effect the radius of the afferent arteriole into the glomerulus has on glomerular filtration rate Methods : 1. Using a glomerulus simulator, the afferent radius was set to .35mm and the efferent radius was set to .40mm 2. A beaker was then filled with blood and the pressure was set at 90mm Hg 3. The glomerulus simulator is then turned on and the blood flows through the afferent arteriole, into the glomerulus, and out of the efferent arteriole 4. During this blood flow, glomerular pressure, glomerular filtration rate, and urine volume were recorded 5. The afferent radius was increased by increments of .05mm and steps 2 and 3 were repeated until a radius of .60mm was achieved 6. All data was recorded Results : Afferent Radius(mm) Glomerular Pressure Glom. Filt. Rate Urine Volume 0.35
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Unformatted text preview: 47.16 26.74 145.57 0.4 49.54 56.28 190.18 0.45 52.57 93.82 213.92 0.5 56.1 137.69 227.49 0.55 59.94 185.24 235.69 0.6 63.83 233.45 240.89-The efferent radius remained at .4mm and the pressure on the volume of blood remained at 90mm Hg for all data recorded Discussion : As the afferent radius was increased in the simulator, the glomerular filtration rate increased. This effect was observed because the arteriole that leads into the glomerulus (afferent) becomes larger while the arteriole that leads out of the glomerulus (efferent) stays the same. In effect, more blood is entering the glomerulus than exiting so the pressue increases, causing the filtration rate to also increase. If the efferent radius were to increase, the pressure inside the glomerulus would decrease as more blood could flow out and the glomerular filtration rate would decrease....
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A+PII Lab 2 - 47.16 26.74 145.57 0.4 49.54 56.28 190.18...

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