10 - Aerobic Respiration C 6 H 12 O 6 O 2 CO 2 H 2 O In...

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Unformatted text preview: Aerobic Respiration C 6 H 12 O 6 + O 2 CO 2 + H 2 O In Prokaryotes Aerobic respiration occurs in the cytoplasm and plasma membrane. In Eukaryotes Aerobic respiration is compartmentalized into the mitochondria. Preparing for TCA Cycle Pyruvate produced by glycolysis is rapidly decarboxylated by a giant complex of three enzymes, called the pyruvate dehydrogenase complex. 13_08_acetylCoA_CO2.jpg The fate of pyruvate depends on the cell energy charge. High energy charge – gluconeogenesis Low energy charge – aerobic respiration Pyruvate enters the outer mitochondrial membrane and is then transported across the inner membrane to the matrix. Conversion to Acetyl CoA is an oxidative decarboxylation Pyruvate Dehydrogenase PDH serves to interconnect the metabolic pathways of glycolysis, gluconeogenesis and fatty acid synthesis to the TCA cycle. Each round of the TCA cycle involves the entry of two carbon atoms (in acetyl CoA), the release of two carbon atoms as carbon dioxide, and the regeneration of oxaloacetate. Oxidation occurs in five steps, including the first step to convert pyruvate to acetyl CoA....
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10 - Aerobic Respiration C 6 H 12 O 6 O 2 CO 2 H 2 O In...

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