Feb 19_Physiological Factors_ Ji Li - Physiological Factors...

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Physiological Factors Related to Drug Absorption
Learning Objectives Explain both passive and active mechanisms of drug absorption from GI Use the Henderson-Hasselbalch equation to calculate the fraction ionized of weakly acidic or a weakly basic drug at a given pH and its significance in drug absorption Explain the first-pass effect and its influence on bioavailability of a drug Understand the characters of various parts in GI tract for drug absorption