Apr21_lecture_Rajnarayanan - Amantadine Also known as...

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Amantadine Also known as Symmetrel (DuPont) 3 ringed symmetric amine Specifically blocks the influenza A M2 protein ion channel. Very effective against influenza A. Must be given within 24 48 hrs of infection: typically in to susceptible patients in anticipation of infection, e.g. nursing homes. Must be adminstered for 10 days Neural side effects led to the discovery that it can alleviate some symptoms of Parkinson’s disease.

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