Chapter_6_Cartilage_And_Bone_Connective_Tissue - Chapter 6...

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I. Cartilage – cushion/pad semi-solid ground substance a. Predominantly collagen fibers and elastic cartilage but still has more rigidity b. Chondrocytes mature cartilage cells that produce i. chondratin sulfate – converts viscous matrix to semi-solid matrix ii. anti-angiogenic molecules – prevent blood vessels development c. Avascular – must get blood supply from surrounding tissues d. Sharks (cartilagous animals) don’t get cancer b/c their anti-angiogenic molecules in skin i. cancer needs blood to produce ii. trying to harvest anti-angeiogenic molecules that may cure cancer e. Lacuna – cavity that holds and protects chondrocytes II. Types of Cartilage a. Hyaline Cartilage i. principle component to fetal skeleton aka precursor to adult skeleton ii. articular surface (ends of adjacent bones w/in a joint) of long bones iii. “costal cartilage” i.e., nose, end of ribs towards sternum b. SCENARIO: If you have open heart surgery, you want them to cut up the costal cartilage by the ribs instead of the bone b/c the cartilage (avascular) will heal faster c. Fibrocartilage – very prominent cartiligous fibers arranged in an irregular pattern i. more resistant/rigid ii. Where: interverbal discs (in larynx) menisci b/t knees, public symphysis (in hips) iii. interverbal discs –support is offered by rings to keep tube open but soft enough to maintain pressure and flexible enough to bend your head iv. “shock absorber” b/t adjacent bones for menisci when you’re walking and public symphysis in males for rough sports v. flexibility in public symphysis in females for child birth d. Elastic Cartilage i. expandability and contractility ii. Where: ear (designed to reflect sound waves), epiglottis of lungs (lid on top of larynx and closes before you swallow so it goes down to the stomach instead of lungs iii. SCENARIO: If you’re really drunk and you’re body’s so slow that the epiglottis doesn’t
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This note was uploaded on 04/17/2008 for the course ANAT BS 212 taught by Professor Zink during the Spring '08 term at University of the Sciences in Philadelphia.

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Chapter_6_Cartilage_And_Bone_Connective_Tissue - Chapter 6...

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