Metabolic Pathway - Bi Sci 001 Monday Announcements Lecture...

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Bi Sci 001 Monday February 24, 1999 Announcements: Lecture notes: Metabolic Pathway A metabolic pathway is a series of orderly reactios that operates under the following rules: 1. Each step is "catalyzed" (quickened) by a specific enzyme. 2. Pathways can be linear, cyclic, or branched. 3. Major pathways are: a. catabolic (degradative) These reactions break down large molecules into smaller ones. (proteins------------------------->amino acids) b. anabolic (biosynthetic) These reactions make large molecules from smaller ones. (amino acids--------------------->proteins) 4. The compounds used in reactions must be in sufficient concentration to permit reactions, but low enough to prevent disruptive side reactions. *****This is why it can be dangerous to take "mega" doses of vitamins or other metabolites without a prescription. They stop acting as a "vitamin" (or mineral, etc.) and start acting as a drug. 5. Most reactions are reversible. Glucose<-------->fructose The rate of the reaction in either direction depends upon the concentration of the reactants. Reversible reactions try to reach "equilibrium" - (when the forward and reverse reactions are occurring at the same rate) There is no NET change in the concentration of products or reactants what a reaction is at equilibrium. Reactions that are not reversible-often involve regulatory enzymes.
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