The Immune System - Bi Sci 001 Monday April 12,1999...

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Bi Sci 001 Monday April 12,1999 Announcements: Review session tonight in 110 Wartick Lecture notes: The Immune System The immune system comprises you body's defense against invasion. There are three lines of defense, each line of defense becoming more specific for a particular invader. First line of defense: barriers Second line of defense: a. phagocytes b. "complement" c. inflammation Third line of defense: a. anitbodies b. cell mediated immunity Barriers (A first line of defense) 1. Intact skin 2. Cilliated mucous membranes a. mucus catches "junk" b. cilia sweep it out. 3. Secretions from exocrine glands on epithelial tissue. (lysozyme in tears) 4. Gastric fluid 5. "Flora" of microbes in the gut and in the vagina in females. They prevent the overgrowth of bacteria. Phagocytes (A second line of defense) These cells originate in bone marrow from stem cells. These include: a. neutrophils b. monocytes (monocytes mature into "big eater" cells called macrophages)
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Phagocytes engulf foreign cells and other substances by endocytosis.
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  • Spring '99
  • Schlegel
  • Bone marrow, 2. 3. 4. 5. 6. 7. 8, foreign cells, myeloid stem cells

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