Lecture4_5 - Fiber Mucus and Membrane Repair Injury of...

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Monosaccharides
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Fig. 5.2
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Raffinose galactose - sucrose connected via an alpha(1-6) glycosidic linkage
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Fig. 5.3
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Glycogen Reserves Used for Heavy Exercise Bicyclists fed different diets for 1-3 days, (all 2800 kcal) then rode to exhaustion. Glycogen data from biopsy
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Fig. 5.5
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Absorption of Glucose by Small Intestine SGLT1: Na-glucose cotransporter GLUT2: Glucose carrier, bidirectional facilitator Lumen of S.I. Epithelial Cell Toward blood
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The Course of Starvation The Course of Starvation
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Health Benefits of Dietary Fiber Reduces constipation by promoting softer, larger stool and regularity. Reduces risk of hemorrhoids, diverticulosis and colon cancer. Binds glucose so slows glucose absorption Binds cholesterol so slows absorption Reduces risk of cardovascular disease
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Fiber - Mucus and Cell Repair Cell injury leads to Ca influx, vesicle fusion that repairs plasma membrane and release of mucus. From Miyake et al., PLoS Sept 2006
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Unformatted text preview: Fiber - Mucus and Membrane Repair Injury of gastric mucous cells Dye for leaky cells Dye for mucus Miyake et al., PLoS Sept 2006 Fig. 5.7Fig. 5.8 Fig. 5.11 Effect of Insulin on Glucose Uptake and Metabolism Fig. 5.12 Diabetes Mellitus--Type 1 • Accounts for 5-10% of cases • Most often juvenile onset • Insulin dependent due to loss of beta cells • Treatment: insulin injections Diabetes Mellitus--Type 2 • Accounts for majority of cases of DM • 80% is associated with obesity • Non-insulin dependent to start • Defective insulin receptors on the cells • Over secretion of insulin to compensate • Leads to beta cells failure • Treatment: medication and diet therapy (weight loss) Extra Material (Optional) pg.142 Table 5.6a Table 5.9 Aspartame (asp-phe) structure incorrect: -CH 2- between NH3 and C-H in asp should not be there. X Table 5.4...
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