AIDS - Bi Sci 001 Wednesday April 21,1999 Announcements...

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Bi Sci 001 Wednesday April 21,1999 Announcements: Lecture notes: AIDS Sexual Transmission: male to male, male to female, female to female. *Women are 20-23 times more likely to receive than transmit the virus in heterosexual transmission. Transmission by blood and blood products: Infected illegal drug "works" Transfusion: Risk- 1 in 50,000 to 1 in 100,000. Factor 8 (Almost no risk now- heat treated or bioengineered now) Mother (Infected) to infant *1/4 infected in mom's uterus. *more are infected by breast milk. HIV (Human Immunodeficiency Virus) HIV is a fragile retrovirus. (retroviruses contain copies of reverse transcriptase which can make DNA from RNA.) Stage of the Disease Process. Exposure: exchange of body fluids which contain enough virus to infect cells. (semen, blood, vaginal fluids, possibly mother's milk) Infection: 1. The virus has a protein on its membrane called gp120. It finds and binds to the protein called CD4 on the surface of a T4 lymphocyte. Also infects monocytes and glial cells in brain.
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AIDS - Bi Sci 001 Wednesday April 21,1999 Announcements...

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