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ASSIGNMENT.docx - Hypogonadism is when the sex glands...

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Hypogonadism is when the sex glands contain insufficient or no sex hormones. The sex glandsare also called gonads. Sex hormones helps to control secondary sex characteristics such asbreast development in women, testicular development in men, and pubic hair growth are allinfluenced by sex hormones[ CITATION Mar18 \l 1033 ](1). The primary hypogonadism cancause either by liver and kidney diseases, autoimmune disorders or genetic disorders such asKlinefelter syndrome which means there is an extra X chromosome that causes irregulartesticular growth, which leads to testosterone underproduction. However, central hypogonadismis the gonads that are regulated by the hypothalamus and pituitary gland are not functioning welldue to infection including HIV that reduces the testosterone by affecting the hypothalamus, thepituitary and the testes, adiposity that can be substantially overweight at any age and geneticdisorder such as the Kallmann syndrome which causes anosmia and red-green colour blindnessdue to theirregular development of the brain region that regulates the hypothalamus. (2019)(2)In 1786,John Hunter transplanted testes into capons to prove the foundation for moderntransplantation medicine, but he ignored endocrine factors. Arnold Adolph Berthold, the founderof endocrinology, proposed internal secretion in 1849. Since testosterone was ineffective, it waspacked into subcutaneous pellets, which obsoleted due to liver toxicity. Klinefelter, Kallmann,

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Luteinizing hormone, hypogonadism, Kallmann syndrome

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