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2007%20Chapter%208%20Taste%20Supplemental%20Images

2007%20Chapter%208%20Taste%20Supplemental%20Images - Ch 8...

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Ch. 8 Chemical senses: Taste
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Taste Bud Taste bud: Receptor cells: Types I, II, III Basal cells Merkel-like cells Species differences Snakes = 0 Duck = 200 Humans = 9-10,000 Catfish = 200,000 Taste pore (top center). Microvilli Apical end of taste receptor cell extend into the taste pore. Transduction Most occurs at apical end of taste receptor cell.
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Taste Receptor Cell Membrane Receptors Apical Surface Ionotropic Metabotropic Depolarization Action Potential Exocytosis Synapse with 1 0 neuron Paracellular pathway (After Glendinning, Chaudhari, & Kinnamon, 2000)
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Na salt transduction Epithelial Na Channels (ENaC) Amiloride sensitive Leak channel Heterotetrameric 2alpha, beta and gamma subunits Na + Depolarization AP Calcium influx Neurotransmitter release Amiloride-insensitive Na + channels Recent evidence: Third type of sodium channel, amiloride- insensitive Na salt transduction Gilbertson & Boughter 2003 Na+ Ca2+
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