Brooker_Chp13P - Chapter 13 Translation of mRNA Deciphering...

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Chapter 13 Translation of mRNA
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Deciphering DNA mRNA sequences translated into polypeptide Triplet mRNA codons  are antiparallel & complementary to tRNA anticodons
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Amino Acids are the Structural Units of Protein Chemical nature of  R confers amino  acid reactivity   Acidic  Basic  Polar  Nonpolar
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Peptide bond formation Directionality of polypeptide synthesis:  N-terminus, C-terminus
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Amino acids used in translation Nonpolar compounds
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Amino acids used in translation Polar compounds
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Peptide – polypeptide structures determined by  proximity of chemical groups
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Polypeptides -> Proteins have function* Multiple polypeptide chains * Cell structure, enzymes, transport, signaling systems. . .  
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‘Equipment’ necessary for translation: mRNA – carries code from DNA gene tRNAs  - transfer appropriate amino acid based on mRNA  codon  Ribosomes  - composed of rRNAs + proteins - small subunit correctly aligns on mRNA - large subunit catalyses peptide bond formation Accessory molecules (‘factors’) and Energy 
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tRNA as the “adaptor” molecule Amino acid attached to 3’ end of tRNA
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Brooker_Chp13P - Chapter 13 Translation of mRNA Deciphering...

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