Brooker_Chp23P - Chapter 23 Drosophila Development Life...

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Chapter 23 Drosophila  Development
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Life cycle of  Drosophila
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Drosophila  development Integrated regulation of gene expression Mitosis . . . Mitosis . . . Pole cells ‘fated’ as gonodal  tissue Nuclear migration occurs Fertilization  Cytoplasmic  membranes form around  nuclei
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Segmentation (cont’d) ultimate adult body pattern 
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Gene expression depends upon cells  receiving chemical signals. Morphogen  gradients define regions w/in egg Maternal effect  gene products Zygotic gene  expression results in  morphogen synthesis & release
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Oocyte + Sperm = Zygote Drosophila  sperm [N]  Fertilization: N + N = 2N [zygote] Oocyte [N] contains mRNA  & proteins expressed from maternal genes [maternal genotype controls!] Maternal effect gene
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Gene expression depends upon receiving  chemical signals.  Transcription, translation and display of cell adhesion molecules  provides physical contact & signaling among cells  Contact thru cell contact triggers further gene expression
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Establishing Axes of Polarity  Head vs. Tail  vs. Top vs. Bottom anterior posterior dorsal ventral
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Brooker_Chp23P - Chapter 23 Drosophila Development Life...

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