A&P II Notes May 1 - Anatomy Physiology II Notes Kidney Function Aldosterone acts on kidney to increase sodium reabsorption acts mainly on the

Anatomy & Physiology II Notes – 5/1/07 Kidney Function • Aldosterone – acts on kidney to increase sodium reabsorption, acts mainly on the distal convoluted tubule and brings about the movement of sodium from the tubule to the peritubular capillaries, leads to the excretion of potassium, release triggered by low sodium concentration in the blood or low BP – occurs through the rennin-angiotensin system o Renin-angiotensin system – in the afferent arteriole, detect low BP and produce renin  leads through angiotensin II production  acts on the adrenals to produce aldosterone o Can’t live without aldosterone • ADH – synthesized in the hypothalamus, travels down the neurons and is stored in the neural hypophysis and upon stimulation it is released, target tissues are the kidneys (mainly the collecting ducts), directs the cells of the collecting ducts to insert proteins into the membrane that act as water pores = aquaporins – water can move down the concentration gradient into the interstitial space and then into the peritubular capillaries, moves by osmosis, urine volume is