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Lecture notes 32

Lecture notes 32 - Lecture 32 Reading for Monday Chapter 21...

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4/18/08 Lecture 32 Reading for Monday: Chapter 21: 438-441 Chapter 22: 466 Chapter 24: 494-495; 499-500 Chapter 25: 518-520 I. Viruses a. Genetic parasites i. Use host’s ribosomes (difference from other parasites) ii. Completely dependent on host iii. Living organisms b. “true” viruses i. Have genome (nucleic acid) can be DNA or RNA ii. Have capsid (protein that surrounds the nucleic acid; protects it) iii. Structure 1. Capsid on outside 2. Nucleic acid on inside a. Only example of life that uses RNA b. Can be single stranded (ss) or double stranded (ds) for either DNA or RNA 3. Envelope a. Lipid bilayer membrane outside of capsid b. Not present in all viruses iv. Viroids 1. Not “true” viruses 2. Infectious particles that only have nucleic acids a. RNA common in plants v. Prions 1. Only have proteins 2. Not “true” viruses II. Biology of Viruses a. Parasites i. Require hosts to make proteins ii. Very efficient 1. Achieve reproduction with minimal components a. Some have fewer than others i. Certain RNA viruses 1. Genome is mRNA (most simple) a. PIcorna i. Colds virus iii. Host ranges 1. Sometimes one species a. Example: HIV 2. Some many species a. Example: flu 3. Every form of life is affected by viruses a. Degree of harm varies i. No harm at all = only genome is replicated: ideal virus ii.
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