Week 11 The Lymphatic System.pdf - NEW ERA UNIVERSITY...

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1NEW ERA UNIVERSITYCollege of NursingCONAP 18 ANATOMY & PHYSIOLOGY LECTUREFirst Semester, AY 2020-2021MODULE 11: The Lymphatic SystemIntroductionThe immune system is the complex collection of cells and organs thatdestroys or neutralizes pathogens that would otherwise cause disease or death.The lymphatic system, for most people, is associated with the immune system tosuch a degree that the two systems are virtually indistinguishable. The lymphaticsystem is the system of vessels, cells, and organs that carries excess fluids to thebloodstream and filters pathogens from the blood. The swelling of lymph nodesduring an infection and the transport of lymphocytes via the lymphatic vessels arebut two examples of the many connections between these critical organ systems.This module intends to deliver the structure and function of the lymphatic system.Key Termsactive immunityimmunity developed from an individual’s own immune systemacute inflammationinflammation occurring for a limited time period; rapidly developingadaptive immune responserelatively slow but very specific and effective immune response controlled bylymphocytesafferent lymphatic vesselslead into a lymph nodeantibody
2antigen-specific protein secreted by plasma cells; immunoglobulinantigenmolecule recognized by the receptors of B and T lymphocytesantigen presentationbinding of processed antigen to the protein-binding cleft of a majorhistocompatibility complex moleculeantigen processinginternalization and digestion of antigen in an antigen-presenting cellantigen receptortwo-chain receptor by which lymphocytes recognize antigenantigenic determinant(also, epitope) one of the chemical groups recognized by a single type oflymphocyte antigen receptorB cellslymphocytes that act by differentiating into an antibody-secreting plasma cellbarrier defensesantipathogen defenses deriving from a barrier that physically prevents pathogensfrom entering the body to establish an infectionbone marrowtissue found inside bones; the site of all blood cell differentiation and maturationof B lymphocytesbronchus-associated lymphoid tissue (BALT)lymphoid nodule associated with the respiratory tractcentral toleranceB cell tolerance induced in immature B cells of the bone marrow
3chemokinesoluble, long-range, cell-to-cell communication moleculechronic inflammationinflammation occurring for long periods of timechylelipid-rich lymph inside the lymphatic capillaries of the small intestinecisterna chylibag-like vessel that forms the beginning of the thoracic ductclass switchingability of B cells to change the class of antibody they produce without altering thespecificity for antigenclonal anergyprocess whereby B cells that react to soluble antigens in bone marrow are madenonfunctionalclonal deletionremoval of self-reactive B cells by inducing apoptosisclonal expansiongrowth of a clone of selected lymphocytesclonal selectionstimulating growth of lymphocytes that have specific receptorsclonegroup of lymphocytes sharing the same antigen receptorcomplementenzymatic cascade of constitutive blood proteins that have antipathogen effects,including the direct killing of bacteria

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