old questions exam#3

old questions exam#3 - Genetics and Cellular Biology (Biol...

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Genetics and Cellular Biology (Biol 204) Name _______________________________ EXAM THREE March 30, 2007 Each question is worth 2 points. Circle the letter that indicates the best answer. a) b) c) d) Chapter 12 H422. A statistically random, unpredictable mutation is called: a) spontaneous. b) induced. c) Conditional d) dynamic. H423. A temperature-sensitive mutation is an example of this kind of mutation: a) gain-of-function. b) ectopic. c) conditional. d) frameshift. H423. A mutation that reduces but does not eliminate the level of gene expression is called a: a) hypomorphic mutation. b) hypermorphic mutation. c) loss-of-function mutation. d) gain of-function. H423. The black markings of a Siamese cat are due to a heat-sensitive mutation. The black color only occurs in those areas of the skin where the skin is cooler and provides what kind of conditions? a) Permissive conditions . b) Restrictive conditions. c) Dynamic conditions. d) Somatic conditions. H424. Which one of these is a transition mutation? a) Change G to C. b) Change T to G. c) Change A to G. d) Change A to C. H425. Which of these will not result in a frame-shift mutation? a) Insertion or deletion of one nucleotide. b) Insertion or deletion of two nucleotides. c) Insertion or deletion of three nucleotides . d) Insertion or deletion of four nucleotides. H425. Many base substitutions in coding regions result in one amino acid being replaced by another. These nonsynonymous mutations are also called: a) silent substitutions. b) nonsense mutations. c) missense mutations . d) frameshift mutations. H425. Many base substitutions in coding regions result in one amino acid being replaced by another. These 1
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nonsynonymous mutations are also called _______ missense______ mutations. H425. Which one of these is a transversion mutation? a) Change G to A. b) Change T to C. c) Change A to G. d) Change A to C . H425. A change from A to C is called a ______ transversion_______ mutation? H426. Homozygotes with single amino acid replacement is in β -globulin have this syndrome (heterozygotes have malaria resistance): a) Huntington disease b) Sickle cell anemia c) Angelman syndrome d) Prader-Willi syndrome H427. The fragile-X syndrome is second only to Down syndrome as a cause of mental retardation. This syndrome spontaneously arises because of a dynamic mutation involving: a) replication slippage of a trinucleotide repeat b) transposable elements. c) smoking. d) radiation. H429. The expansion of trinucleotide repeats, by a process called ___ replication ____ ____ slippage __ is responsible for such diseases as the fragile-X syndrome and Huntington disease. H430. DNA transposons use this mechanism: a) cut-and-paste transposition. b)
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This note was uploaded on 04/18/2008 for the course BIOL 204 taught by Professor Auger during the Spring '08 term at SD State.

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old questions exam#3 - Genetics and Cellular Biology (Biol...

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