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Unformatted text preview: Genetics and Cellular Biology (Biol 204) Name _______________________________ EXAM THREE April 4, 2008 Each question is worth 2 points. Circle the letter that indicates the best answer. a) b) c) d) H&amp;J 12 H422. A statistically random, unpredictable mutation is called: a) spontaneous. b) induced. c) Conditional d) dynamic. H422. This term specifically refers to a mutation that is not transmitted to a progeny but produces an organism that is a mosaic of mutant and normal tissue: a) somatic mutation. b) germ-line mutation. c) conditional mutation. d) gain-of-function mutation. H423. A temperature-sensitive mutation is an example of this kind of mutation: a) gain-of-function. b) ectopic. c) conditional. d) frameshift. H423. A mutation that reduces but does not eliminate the level of gene expression is called a: a) hypomorphic mutation. b) hypermorphic mutation. c) loss-of-function mutation. d) gain of-function. H423. The black markings of a Siamese cat are due to a heat-sensitive mutation. The black color only occurs in those areas of the skin where the skin is cooler and provides what kind of conditions? (Caution: glossary has it wrong). a) Permissive conditions . b) Restrictive conditions. c) Dynamic conditions. d) Somatic conditions. H424. Which one of these is a transition mutation? a) Change G to C. b) Change T to G. c) Change A to G. d) Change A to C. H425. Which of these is a synonymous substitution? a) An extra base is inserted into an intron. b) A transition in the third position of a codon does not change the amino acid specified. c) A change in the amino acid has no effect upon the functioning of the protein. d) One pyrimidine is exchanged for another or one purine is exchanged for another. H425. A synonymous substitution refers to a molecular mutation where: a) an extra base is inserted into an intron. b) a transition in the third position of a codon does not change the amino acid specified. 1 c) a change in the amino acid has no effect upon the functioning of the protein. d) one pyrimidine is exchanged for another or one purine is exchanged for another. H425. Which of these will not result in a frame-shift mutation? a) Insertion or deletion of one nucleotide. b) Insertion or deletion of two nucleotides. c) Insertion or deletion of three nucleotides . d) Insertion or deletion of four nucleotides. H425. Many base substitutions in coding regions result in one amino acid being replaced by another. These nonsynonymous mutations are also called: a) silent substitutions. b) nonsense mutations. c) missense mutations . d) frameshift mutations. H425. Many base substitutions in coding regions result in one amino acid being replaced by another. These nonsynonymous mutations are also called _______ missense______ mutations....
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