Jan 21 - Dementia general label referring to a syndrome 3...

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Dementia - general label referring to a syndrome 3 properties: 1. global cognitive decline- all cognitive domains are affected; it is not merely a focal disorder affecting only memory, or language, or spatial cognition 2. progressive- dementias worsen over time; this differentiates dementia from static but global cognitive disorders such as traumatic brain injury 3. irreversible- historically, dementias have been characterized as untreatable, thereby differentiating them from delirium which is similar in symptom picture but treatable -Qualifications to the above: 1) dementias can begin as a focal disorder (e.g., in 80% of Alzheimer’s disease memory is affected before other cognitive domains show significant decline 2) there are plateaus in progression (can be months to 1-2 years in length): however, over time, the disorder will worsen 3) although classically defined as irreversible, we are confident that, eventually, treatments will be found Alzheimer’s Disease (AD): 1. the most common of all the dementias 2. requires a
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