Exam III 2005 - Name: General Biochemistry Tuesday,...

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Name: General Biochemistry Tuesday, December 2oth, 2005 4:OO-6:00 PM Put your name and identification number on the answer sheet. Mark only one answer for each question on the answer sheet. Use only the pencil provided for the examination. Do not fold or bend the answer sheet. Make sure you have 1 1 question pages. Read each question carehlly. 1. Which of the following are polar lipids contain ceramide? A. Phosphatidylcholine B. Phosphatidylethanolamine C. Sphingomyelin D. Cardiolipin E. All glycerolphospholipids 2. The naturally occurring fatty acid 22:2 A"I2 A. Will have double bonds in cis and trans conformations B. Is an omega- 3 fatty acid C. Will be very soluble in water D. Will have a higher melting point than fatty acid 22: 1 a9 E. Will have a higher melting point than fatty acid 16:2 A9)I2
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For questions 3-4. Match the following to the structure below: A. Phosphatidylinisitol B. Sphingomyelin C. Triacyglceride D. Phosphatidylcholine E. Phosphatidylethanolamine F. Phosphatidylserine G. Cardiolipin H. Plasmologen May be 1 C-4 or 0 C-4 and C-5 0 Ctip CH:, I ! I <-7,,+ Long aliphat~c chains
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5. In order to obtain choline you will have to cleave phosphatidylcholine with which enzyme A. Phospholipase A, B. Phospholipase A2 C. Phospholipase C D. Phospholipase D E. Any of the above 6. Lipids serve the following functions A. Major storage form of energy as diglycerides B. Important structural component as amphiphilic lipids C. Intracellular signaling as triglycerides D. Major storage form of energy as amphiphilic lipids E. Intercellular signaling as triglycerides 7. All of the following statement is true regarding the lipids in the membranes, except A. They include triglycerides B. They contain phosphatidylinositol C. They constitute the lipid bilayer D. The composition of the lipids varies among various membranes of the cell. E. Membrane fluidity is influenced by the nature of the fatty acids on the lipids 8. All of the following statements concerning artificial membranes are correct except A. During the formation of the phospholipid bilayer entropy is increased. B. The most stable artificial phospholipid structure in an aqueous environment is the liposome. C. In a micelle, the cross section of the head group of the individual phospholipid unit is greater than that of the side chain. D. Hydrophobic interactions drive the formation of the phospholipid bilayer. E. Disulfide bonds stabilize the head groups of the phospholipids in a liposome. 9. Choose the correct statement concerning biological membranes. A. They are asymmetric covalent assemblies of protein and lipid molecules. B. The thickness of most membranes is between 500 and 1000 A. C. The anionic phospholipids, phosphatidylserine and phosphatidylinositol are enriched in the outer phospholipid monolayer. D.
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This note was uploaded on 04/18/2008 for the course BIOC 1010 taught by Professor Zhang during the Fall '07 term at New York Medical College.

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Exam III 2005 - Name: General Biochemistry Tuesday,...

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