In the latter case plasma and tissue oncotic

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Unformatted text preview: ot; to proteins have a very low s . In the latter case, plasma and tissue oncotic pressures may have a negligible influence on the net driving force. Tissue (interstitial) Oncotic Pressure (PT) The oncotic pressure of the interstitial fluid depends on the interstitial protein concentration and the reflection coefficient of the capillary wall. The more permeable the capillary barrier is to proteins, the higher the interstitial oncotic pressure. This pressure is also determined by the amount of fluid filtration into the interstitium. For example, increased capillary filtration decreases interstitial protein concentration and reduces the oncotic pressure. This effect of filtration on protein concentration also serves as a mechanism to limit capillary filtration. In a "typical" tissue, tissue oncotic pressure is about 5 mmHg (i.e., much lower than capillary plasma oncotic pressure). 7 Pulmonary Circulation Microcirculation Structure and Function The microcirculation is comprised of arterioles, capillaries, ve...
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This note was uploaded on 04/18/2008 for the course PHYS 1010 taught by Professor Thompson during the Fall '07 term at New York Medical College.

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