10.23 - Sabban - Enzymology of RNA Synthesis

10.23 - Sabban - Enzymology of RNA Synthesis -...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Transcription Biosynthesis of RNA Dr. Sabban 10/23/2007 1 DNA RNA Polypeptide Functional protein Transcription Translation Folding Template (antisense) strand Coding (sense) strand 2 Major classes of RNA Prokaryotes rRNA: 16S, 23S, 5S (80% of cellular RNA); stable tRNA: 4S (15% of cellular RNA); stable mRNA: heterogeneous (5% of cellular RNA); rapid turnover Eukaryotes rRNA: 18S, 28S, 5S, 5.8S (80% of cellular RNA); stable tRNA: 4S (15% of cellular RNA); stable mRNA: heterogeneous (2-5% of cellular RNA); rapid turnover 3 snRNA: Low M.W. nucleus located RNAs involved in splicing; rich in U s RNA component of SRP Micro RNA (miRNA) small (about 21 nucleotides) non coding RNA complementary to mRNA and inhibit translation Small interfering RNA (siRNA) small RNAs that bind mRNA and facilitate its degradation RNA component of telemerase Additional Small RNAs in Eukaryotes 4 RNA polymerase will read the top (template, antisense -) strand 3...
View Full Document

Page1 / 12

10.23 - Sabban - Enzymology of RNA Synthesis -...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online