04.10 - Sabban - Lipoproteins and Lipid Transport

04.10 Sabban- - Structure of Lipoproteins 1 2 Composition of Blood Lipoproteins 3 4 5 6 Chylomicrons 7 I 8 9 VLDL Very Low Density Lipoprotein 10

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Unformatted text preview: Structure of Lipoproteins 1 2 Composition of Blood Lipoproteins 3 4 5 6 Chylomicrons 7 I 8 9 VLDL Very Low Density Lipoprotein 10 Synthesis of VLDL in Liver 11 Delivery of Triglycerides of VLDL 12 LDL Low Density Lipoprotein 13 Conversion of VLDL to IDL and LDL 14 15 LDL RECEPTOR 16 Uptake and Effect of LDL on Peripheral Cells 17 18 RNA Editing of Apo B 19 20 21 Plaques Formation in Vessel Walls 22 HDL High Density Lipoprotein 23 24 Functions of HDL •Circulating reservoir of ApoC-II - the activator of lipoprotein lipase •Remove free cholesterol from extrahepatic tissues by esterifying it - LCAT •Transfer cholesterol esters to VLDL and LDL in exchange for triglcerides •Carrying cholesterol esters to the liver, where HDL is degraded and cholesterol released. 25 Exchange of Apoproteins between HDL and Chylomicrons 26 HDL 27 28 Exchange of Cholesterol between VDL and HDL 29 30 31 Functions of HDL •Circulating reservoir of ApoC-II - the activator of lipoprotein lipase •Remove free cholesterol from extrahepatic tissues by esterifying it...
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This note was uploaded on 04/18/2008 for the course PHYS 1010 taught by Professor Thompson during the Fall '07 term at New York Medical College.

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04.10 Sabban- - Structure of Lipoproteins 1 2 Composition of Blood Lipoproteins 3 4 5 6 Chylomicrons 7 I 8 9 VLDL Very Low Density Lipoprotein 10

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