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Unformatted text preview: CHEMISTRY OF INHERITANCE Chap. ~: ~d..-J,..f"),. Chryt-k-v cr -Looking at gene from the molecular level. -Previous definiti0n of gene (unit of inheritance) is good for Mendelian Genetics, but need more specific definition for molecular.
-Gene: sequence of nucleotide bases in DNA molecule that "codes" for specific protein. -Must look at DNA for inheritance information DNA (deoxyribonucleic acid)- genetic material in all living organisms -made in nucleus; housed in nucleus (some in chloroplasts and mitochondria) -Structure: proposed by Watson & Crick in 1953 (received Nobel Prize for such an important description) -3 components:
(a) (b) 5-carbon sugar- deoxyribose sugar phosphate group 1 of 4 different nitrogenous bases: *Purines: two six-sided rings (A & G) NUCLEOTIDE (c) 4 fyft> - . Adenine (A), Thymine (T), Guanine (G), Cytosine (C) k' i( d /(If1 .~ DO 'I LO l:7 0L,.. ) --J:r;T
~ of Df'lfo, *Pyrimidines: one six-sided ring (T & C ) O nitrogenous bases pair in a specific way: complementary base pairing
A T tJN4
VI /S and G C *concentration of A=T and C=G DO/boLe ~5/P
~ ./' "e He/if of
Nv<.[fbMej i,i II V.i1l11 Oi1CJ -Function:information storage DNA = genetic blueprint; contains all info. necessary to make a new organism Info is stored in the sequence of bases of DNA molecule ...
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