Recitation__9-handout-Simona

Recitation__9-handout-Simona - TA: Simona Tescu 7.05...

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TA: Simona Tescu 04/16/2008 7.05 Recitation email: tescu@mit.edu 1/7 RECITATION #9 Today we will cover: - Regulation of glycolysis - Utilization of sugars other than glucose - Parts of the TCA cycle Know mechanism of the following reactions and the structure and role of the cofactors: - Mutases - Pyruvate decarboxylase (thiamine-PP cofactor) - Pyruvate dehydrogenase complex (pyruvate oxidation particle) o Pyruvate decarboxylase: contains thiamine-PP o Dihydrolipoyl transferase: contains lipoic acid and a binding site for CoA o Dihydrolipoyl hydrogenase: contains covalently bound FAD and binds NAD+ Thiamine-PP Coenzyme A (CoA) FAD/ FADH 2 Lipoic acid NAD+/ NADH - More insight into the phosphoglycerate mutase mechanism
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TA: Simona Tescu 04/16/2008 7.05 Recitation email: tescu@mit.edu 2/7 Question 1) Regulation of glycolysis Question 2) What are the effects on glycolysis if high concentrations of the following were present? Compound
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Recitation__9-handout-Simona - TA: Simona Tescu 7.05...

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